BDBM581757 US11512087, Example 1

SMILES Cc1nn(C)cc1Nc1nc(N)c2c(-c3ccc4[nH]ccc4c3)nn(C(C)C)c2n1

InChI Key InChIKey=HXKNWNXWDIVAGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 581757   

TargetProtein-tyrosine kinase 6(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 581757BDBM581757(US11512087, Example 1)
Affinity DataIC50: 2.10nMAssay Description:Measurement of an inhibitory activity on Brk enzyme was performed by using LanthaScreen (registered trademark) system (Invitrogen) in accordance with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetTyrosine-protein kinase Lck(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 581757BDBM581757(US11512087, Example 1)
Affinity DataIC50: 1.00E+4nMAssay Description:Tyrosine phosphorylation of Lck was performed by using Z′-LYTE Kinase Assay Kit-Tyr 2 Peptide (Invitrogen) containing the following reagents (T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent