BDBM581806 US11512087, Example 4-3

SMILES CC(C)n1nc(-c2ccc(F)c3[nH]ncc23)c2c(N)nc(Nc3ccc(cc3F)S(C)(=O)=O)nc12

InChI Key InChIKey=OZLWUXZCYMFSKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 581806   

TargetProtein-tyrosine kinase 6(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM581806(US11512087, Example 4-3)
Affinity DataIC50: 8.5nMAssay Description:Measurement of an inhibitory activity on Brk enzyme was performed by using LanthaScreen (registered trademark) system (Invitrogen) in accordance with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetTyrosine-protein kinase Lck(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM581806(US11512087, Example 4-3)
Affinity DataIC50: 2.50E+3nMAssay Description:Tyrosine phosphorylation of Lck was performed by using Z′-LYTE Kinase Assay Kit-Tyr 2 Peptide (Invitrogen) containing the following reagents (T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent