BDBM582035 Preparation of (2S,4R)-1-((S)-2-(2-(2-(2-(4-(((E)-4-((6-chloro-2-methyl-2H-indazole)-5-yl)imino)-2,6-dioxy-3-(2,4,5-trifluorobenzyl)-1,3,5-triazin-1-yl)methyl)-1H-1,2,3-Triazol-1-yl)ethoxy)ethoxy)acetamido)-3,3-dimethylbutyryl)-4-hydroxy-N-(4-(4-Methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide::US11518759, Compound 8

SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCn2cc(Cn3c(=O)[nH]\c(=N/c4cc5cn(C)nc5cc4Cl)n(Cc4cc(F)c(F)cc4F)c3=O)nn2)C(C)(C)C)cc1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 582035   

TargetReplicase polyprotein 1a(SARS-CoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM582035(Preparation of (2S,4R)-1-((S)-2-(2-(2-(2-(4-(((E)-...)
Affinity DataIC50: <100nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent