BDBM582446 US11518764, Compound I-459

SMILES C[C@H]1CN(CC(O)CCO)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2ncn(C)c3=O)c(Cl)c(F)n1

InChI Key InChIKey=MMTQZXDURFKWJI-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 582446   

TargetB-cell lymphoma 6 protein(Human)
Ontario Institute For Cancer Research (Oicr)

US Patent
LigandPNGBDBM582446(US11518764, Compound I-459)
Affinity DataKd:  6.55nMAssay Description:SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent