BDBM585044 US11529347, Compound 22

SMILES CC1(CN)CCN(CC1)c1cnc2c(n[nH]c2n1)-c1ncccc1Cl

InChI Key InChIKey=NEFRHDAKVJXJIO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585044   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Relay Therapeutics

US Patent
LigandPNGBDBM585044(US11529347, Compound 22)
Affinity DataIC50: 5.50E+4nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
US Patent