BDBM585332 6-ethyl-5-(4-(5-methylpyridin-2- yl)piperazin-1-yl)pyrimidine- 2,4-diamine::US11530198, Example 45

SMILES CCc1nc(N)nc(N)c1N1CCN(CC1)c1ccc(C)cn1

InChI Key InChIKey=VSUAJVFBSPOMSQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 585332   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM585332(US11530198, Example 45 | 6-ethyl-5-(4-(5-methylpyr...)
Affinity DataIC50: 5.89nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
US Patent

TargetDihydrofolate reductase(Human)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM585332(US11530198, Example 45 | 6-ethyl-5-(4-(5-methylpyr...)
Affinity DataIC50: 794nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
US Patent