BDBM585393 6-[3-(1,1-Difluoroethyl)phenyl]-1-(3-pyridylmethyl)pyrazolo[4,3- b]pyridine::US11530210, Example 12::US11530210, Example 163

SMILES FC(F)(F)c1cccc(c1)-c1cnc2cnn(Cc3cccnc3)c2c1

InChI Key InChIKey=GKZOJCUTFGGEQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 585393   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM585393(US11530210, Example 163 | 6-[3-(1,1-Difluoroethyl)...)
Affinity DataIC50: 26nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM585393(US11530210, Example 163 | 6-[3-(1,1-Difluoroethyl)...)
Affinity DataIC50: 90nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent