BDBM585435 3-[[6-[3-(Difluoromethyl)-4-fluoro-phenyl]pyrazolo[4,3-b]pyridin-1- yl]methyl]isoxazole::US11530210, Example 51

SMILES FC(F)c1cc(ccc1F)-c1cnc2cnn(Cc3ccon3)c2c1

InChI Key InChIKey=PVOQMOZBTUTFRC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585435   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM585435(US11530210, Example 51 | 3-[[6-[3-(Difluoromethyl)...)
Affinity DataIC50: 23nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent