BDBM585508 2-[[6-[3-(Difluoromethyl)-4-fluoro-phenyl]-3-fluoro-pyrazolo[4,3- b]pyridin-1-yl]methyl]-5-methyl-1,3,4-thiadiazole::US11530210, Example 123

SMILES Cc1nnc(Cn2nc(F)c3ncc(cc23)-c2ccc(F)c(c2)C(F)F)s1

InChI Key InChIKey=CIOBCKYBUPDDOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585508   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM585508(US11530210, Example 123 | 2-[[6-[3-(Difluoromethyl...)
Affinity DataIC50: 42nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent