BDBM585514 2-(Difluoromethyl)-5-[[6-[3-(difluoromethyl)-4-fluoro- phenyl]pyrazolo[4,3-b]pyridin-1-yl]methyl]-1,3,4-thiadiazole::US11530210, Example 129

SMILES FC(F)c1nnc(Cn2ncc3ncc(cc23)-c2ccc(F)c(c2)C(F)F)s1

InChI Key InChIKey=PSPAHUFEQBMOSI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585514   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM585514(US11530210, Example 129 | 2-(Difluoromethyl)-5-[[6...)
Affinity DataIC50: 17nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent