BDBM585580 6-(3-Chloro-4-fluoro-phenyl)-1-[(5-fluoro-3- pyridyl)methyl]pyrazolo[4,3-b]pyridine::US11530210, Example 195

SMILES Fc1cncc(Cn2ncc3ncc(cc23)-c2ccc(F)c(Cl)c2)c1

InChI Key InChIKey=YOEBHXAPPNTAQD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585580   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM585580(US11530210, Example 195 | 6-(3-Chloro-4-fluoro-phe...)
Affinity DataIC50: 25nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent