BDBM585592 6-[3-(Difluoromethyl)-4-fluoro-phenyl]-1-[(5-methoxy-3- pyridyl)methyl]pyrazolo[4,3-b]pyridine::US11530210, Example 207

SMILES COc1cncc(Cn2ncc3ncc(cc23)-c2ccc(F)c(c2)C(F)F)c1

InChI Key InChIKey=PTPHUJLNORVRIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585592   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM585592(US11530210, Example 207 | 6-[3-(Difluoromethyl)-4-...)
Affinity DataIC50: 28nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent