BDBM585608 6-[3-(Difluoromethoxy)-4-fluoro-phenyl]-1-(3- pyridylmethyl)pyrazolo[4,3-b]pyridine::US11530210, Example 223

SMILES FC(F)Oc1cc(ccc1F)-c1cnc2cnn(Cc3cccnc3)c2c1

InChI Key InChIKey=SKTBHOWMEXXGRB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585608   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM585608(US11530210, Example 223 | 6-[3-(Difluoromethoxy)-4...)
Affinity DataIC50: 38nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent