BDBM585610 6-[3-(Difluoromethoxy)-4-fluoro-phenyl]-1-[(5-fluoro-3- pyridyl)methyl]pyrazolo[4,3-b]pyridine::US11530210, Example 225

SMILES FC(F)Oc1cc(ccc1F)-c1cnc2cnn(Cc3cncc(F)c3)c2c1

InChI Key InChIKey=PACAOBGJGOLPHV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585610   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM585610(US11530210, Example 225 | 6-[3-(Difluoromethoxy)-4...)
Affinity DataIC50: 39nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent