BDBM585636 1-[(5-Fluoro-3-pyridyl)methyl]-6-(3,4,5-trifluorophenyl)pyrazolo[4,3- b]pyridine::US11530210, Example 251

SMILES Fc1cncc(Cn2ncc3ncc(cc23)-c2cc(F)c(F)c(F)c2)c1

InChI Key InChIKey=ATMXBHJDBUAPJV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585636   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM585636(US11530210, Example 251 | 1-[(5-Fluoro-3-pyridyl)m...)
Affinity DataIC50: 25nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent