BDBM585886 US11530237, Compound 45::US11542297, Compound 45

SMILES COc1cccc2n(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nnc12

InChI Key InChIKey=ADPDLMAIIYESON-HZLKNYGISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 585886   

TargetGamma-aminobutyric acid (GABA) B receptor 1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM585886(US11530237, Compound 45 | US11542297, Compound 45)
Affinity DataIC50: <10nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM585886(US11530237, Compound 45 | US11542297, Compound 45)
Affinity DataIC50: <10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent