BDBM587569 5-(2-ethoxy-3-pyridyl)-1-(oxetan-3-yl)-7- pyrrolidin-1-yl-pyrazolo[4,3-b]pyridine::US11535611, Example 4

SMILES CCOc1ncccc1-c1cc(N2CCCC2)c2n(ncc2n1)C1COC1

InChI Key InChIKey=MZOCQVQIWJPCHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 587569   

LigandPNGBDBM587569(5-(2-ethoxy-3-pyridyl)-1-(oxetan-3-yl)-7- pyrrolid...)
Affinity DataIC50: 95nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587569(5-(2-ethoxy-3-pyridyl)-1-(oxetan-3-yl)-7- pyrrolid...)
Affinity DataIC50: 641nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent