BDBM587583 5-(2-ethoxy-3-pyridyl)-1-isopropyl-N- [[(2R)-tetrahydrofuran-2- yl]methyl]pyrazolo[4,3-b]pyridin-7-amine::US11535611, Example 7

SMILES CCOc1ncccc1-c1cc(NC[C@H]2CCCO2)c2n(ncc2n1)C(C)C

InChI Key InChIKey=HIAMRTZPJJKUES-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 587583   

LigandPNGBDBM587583(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N- [[(2R)-tetra...)
Affinity DataIC50: 83nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587583(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N- [[(2R)-tetra...)
Affinity DataIC50: 449nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587583(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N- [[(2R)-tetra...)
Affinity DataIC50: 1.71E+3nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent