BDBM587593 5-(2-ethoxy-3-pyridyl)-1-isopropyl-N- tetrahydropyran-4-yl-pyrazolo[4,3- b]pyridin-7-amine::US11535611, Example 10

SMILES CCOc1ncccc1-c1cc(NC2CCOCC2)c2n(ncc2n1)C(C)C

InChI Key InChIKey=GLBTTXQMDAGNOY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 587593   

LigandPNGBDBM587593(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N- tetrahydropy...)
Affinity DataIC50: 126nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587593(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N- tetrahydropy...)
Affinity DataIC50: 2.67E+3nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent