BDBM587594 5-(2-ethoxy-3-pyridyl)-1-isopropyl-N- [trans-4-methoxytetrahydrofuran-3- yl]pyrazolo[4,3-b]pyridin-7-amine::US11535611, Example 11

SMILES CCOc1ncccc1-c1cc(N[C@@H]2COC[C@H]2OC)c2n(ncc2n1)C(C)C

InChI Key InChIKey=ODAVXTCJLMTDFI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 587594   

LigandPNGBDBM587594(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N- [trans-4-met...)
Affinity DataIC50: 82nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587594(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N- [trans-4-met...)
Affinity DataIC50: 575nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587594(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N- [trans-4-met...)
Affinity DataIC50: 1.48E+3nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent