BDBM587691 1-isopropyl-3,6-dimethyl-5-phenyl- pyrazolo[4,3-b]pyridine::US11535611, Example 60

SMILES CC(C)n1nc(C)c2nc(c(C)cc12)-c1ccccc1

InChI Key InChIKey=NHTZYYDADSWQFF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 587691   

LigandPNGBDBM587691(1-isopropyl-3,6-dimethyl-5-phenyl- pyrazolo[4,3-b]...)
Affinity DataIC50: 122nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587691(1-isopropyl-3,6-dimethyl-5-phenyl- pyrazolo[4,3-b]...)
Affinity DataIC50: 198nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587691(1-isopropyl-3,6-dimethyl-5-phenyl- pyrazolo[4,3-b]...)
Affinity DataIC50: 225nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent