BDBM587694 5-(2-ethoxy-3-pyridyl)-1-isopropyl-3,6- dimethyl-pyrazolo[4,3-b]pyridine::US11535611, Example 63

SMILES CCOc1ncccc1-c1nc2c(C)nn(C(C)C)c2cc1C

InChI Key InChIKey=BFRDRFVRTDDXOO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 587694   

LigandPNGBDBM587694(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3,6- dimethyl-p...)
Affinity DataIC50: 16nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587694(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3,6- dimethyl-p...)
Affinity DataIC50: 86nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587694(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3,6- dimethyl-p...)
Affinity DataIC50: 175nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent