BDBM587695 1-isopropyl-3,6-dimethyl-5-(2-propoxy-3- pyridyl)pyrazolo[4,3-b]pyridine::US11535611, Example 64

SMILES CCCOc1ncccc1-c1nc2c(C)nn(C(C)C)c2cc1C

InChI Key InChIKey=GLUMAFSYFKCMND-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 587695   

LigandPNGBDBM587695(1-isopropyl-3,6-dimethyl-5-(2-propoxy-3- pyridyl)p...)
Affinity DataIC50: 25nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587695(1-isopropyl-3,6-dimethyl-5-(2-propoxy-3- pyridyl)p...)
Affinity DataIC50: 118nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587695(1-isopropyl-3,6-dimethyl-5-(2-propoxy-3- pyridyl)p...)
Affinity DataIC50: 220nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent