BDBM587696 5-(2-ethoxy-3-pyridyl)-1-isopropyl-N,3- dimethyl-pyrazolo[4,3-b]pyridin-7-amine::US11535611, Example 65

SMILES CCOc1ncccc1-c1cc(NC)c2n(nc(C)c2n1)C(C)C

InChI Key InChIKey=ABXBWGWLDQBUBP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 587696   

LigandPNGBDBM587696(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N,3- dimethyl-p...)
Affinity DataIC50: 7nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587696(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N,3- dimethyl-p...)
Affinity DataIC50: 50nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587696(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N,3- dimethyl-p...)
Affinity DataIC50: 111nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent