BDBM587697 5-(2-ethoxy-3-pyridyl)-N-ethyl-1-isopropyl- 3-methyl-pyrazolo[4,3-b]pyridin-7-amine::US11535611, Example 66

SMILES CCNc1cc(nc2c(C)nn(C(C)C)c12)-c1cccnc1OCC

InChI Key InChIKey=IEMFUUSWJIFFAI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 587697   

LigandPNGBDBM587697(5-(2-ethoxy-3-pyridyl)-N-ethyl-1-isopropyl- 3-meth...)
Affinity DataIC50: 5nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587697(5-(2-ethoxy-3-pyridyl)-N-ethyl-1-isopropyl- 3-meth...)
Affinity DataIC50: 60nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587697(5-(2-ethoxy-3-pyridyl)-N-ethyl-1-isopropyl- 3-meth...)
Affinity DataIC50: 161nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent