BDBM587698 (+-)-5-[[[5-(2-ethoxy-3-pyridyl)-1-isopropyl- 3-methyl-pyrazolo[4,3-b]pyridin-7- yl]amino]methyl]-1-methyl-pyrrolidin-2- one::US11535611, Example 67

SMILES CCOc1ncccc1-c1cc(NCC2CCC(=O)N2C)c2n(nc(C)c2n1)C(C)C

InChI Key InChIKey=GBCXKXMTXPRTLX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 587698   

LigandPNGBDBM587698((+-)-5-[[[5-(2-ethoxy-3-pyridyl)-1-isopropyl- 3-me...)
Affinity DataIC50: 11nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587698((+-)-5-[[[5-(2-ethoxy-3-pyridyl)-1-isopropyl- 3-me...)
Affinity DataIC50: 70nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587698((+-)-5-[[[5-(2-ethoxy-3-pyridyl)-1-isopropyl- 3-me...)
Affinity DataIC50: 106nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent