BDBM587701 5-(2-ethoxy-3-pyridyl)-1-isopropyl- pyrazolo[4,3-b]pyridine::US11535611, Example 70

SMILES CCOc1ncccc1-c1ccc2n(ncc2n1)C(C)C

InChI Key InChIKey=ZDEYBOGYJCESDB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 587701   

LigandPNGBDBM587701(5-(2-ethoxy-3-pyridyl)-1-isopropyl- pyrazolo[4,3-b...)
Affinity DataIC50: 99nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587701(5-(2-ethoxy-3-pyridyl)-1-isopropyl- pyrazolo[4,3-b...)
Affinity DataIC50: 836nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587701(5-(2-ethoxy-3-pyridyl)-1-isopropyl- pyrazolo[4,3-b...)
Affinity DataIC50: 2.17E+3nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent