BDBM587702 2-(2-ethoxy-3-pyridyl)-6-isopropyl-3,8- dimethyl-imidazo[1,5-a]pyrimidine::US11535611, Example 71

SMILES CCOc1ncccc1-c1nc2c(C)nc(C(C)C)n2cc1C

InChI Key InChIKey=CEXMMUZLWOYRDY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 587702   

LigandPNGBDBM587702(2-(2-ethoxy-3-pyridyl)-6-isopropyl-3,8- dimethyl-i...)
Affinity DataIC50: 17nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587702(2-(2-ethoxy-3-pyridyl)-6-isopropyl-3,8- dimethyl-i...)
Affinity DataIC50: 74nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587702(2-(2-ethoxy-3-pyridyl)-6-isopropyl-3,8- dimethyl-i...)
Affinity DataIC50: 99nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent