BDBM587703 2-(2-ethoxy-3-pyridyl)-6-isopropyl-8- methyl-imidazo[1,5-a]pyrimidine::US11535611, Example 72

SMILES CCOc1ncccc1-c1ccn2c(nc(C)c2n1)C(C)C

InChI Key InChIKey=WIOSRHGIFUMFNQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 587703   

LigandPNGBDBM587703(2-(2-ethoxy-3-pyridyl)-6-isopropyl-8- methyl-imida...)
Affinity DataIC50: 34nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587703(2-(2-ethoxy-3-pyridyl)-6-isopropyl-8- methyl-imida...)
Affinity DataIC50: 96nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587703(2-(2-ethoxy-3-pyridyl)-6-isopropyl-8- methyl-imida...)
Affinity DataIC50: 213nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent