BDBM587704 6-cyclobutyl-2-(2-ethoxy-3-pyridyl)-8- methyl-imidazo[1,5-a]pyrimidine::US11535611, Example 73::US11535611, Example 74

SMILES CCOc1ncccc1-c1ccn2c(nc(C)c2n1)C1CCC1

InChI Key InChIKey=BNYIEPJRYJQTHM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 587704   

LigandPNGBDBM587704(6-cyclobutyl-2-(2-ethoxy-3-pyridyl)-8- methyl-imid...)
Affinity DataIC50: 121nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587704(6-cyclobutyl-2-(2-ethoxy-3-pyridyl)-8- methyl-imid...)
Affinity DataIC50: 296nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587704(6-cyclobutyl-2-(2-ethoxy-3-pyridyl)-8- methyl-imid...)
Affinity DataIC50: 394nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587704(6-cyclobutyl-2-(2-ethoxy-3-pyridyl)-8- methyl-imid...)
Affinity DataIC50: 1.18E+3nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587704(6-cyclobutyl-2-(2-ethoxy-3-pyridyl)-8- methyl-imid...)
Affinity DataIC50: 1.55E+3nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM587704(6-cyclobutyl-2-(2-ethoxy-3-pyridyl)-8- methyl-imid...)
Affinity DataIC50: 2.09E+3nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent