BDBM588095 US11542246, Compound 5

SMILES COc1nc2c(OCC3CC(F)(F)C(=O)N3)cccc2cc1C(N)=O

InChI Key InChIKey=LBEAYFURUOTXQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 588095   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Patent

US Patent
LigandPNGBDBM588095(US11542246, Compound 5)
Affinity DataIC50: 100nMAssay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712). IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Serine/Threonine...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 1(Human)
Merck Patent

US Patent
LigandPNGBDBM588095(US11542246, Compound 5)
Affinity DataIC50: 3.00E+3nMAssay Description:IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712)). In this assay, IRAK-1 hydrolyses ATP and autophosphorylates. Measurement of I...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent