BDBM588178 US11542251, Compound 2

SMILES O=C(CCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12)N1CCC(CC1)c1cc(NC(=O)c2cccc(n2)-c2ccn[nH]2)n(n1)-c1ccccn1

InChI Key InChIKey=FQGLEOSEPJEJPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 588178   

TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588178(US11542251, Compound 2)
Affinity DataIC50: 42nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588178(US11542251, Compound 2)
Affinity DataIC50: 44nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent