BDBM588179 US11542251, Compound 3

SMILES O=C(CCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12)N1CCC(CC1)c1cnn(c1NC(=O)c1cccc(n1)-c1cc[nH]c1)-c1ccccn1

InChI Key InChIKey=VVQWKIHKNXGJKG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 588179   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588179(US11542251, Compound 3)
Affinity DataIC50: 18nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588179(US11542251, Compound 3)
Affinity DataIC50: 40nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent