BDBM588181 US11542251, Compound TL1

SMILES CC(C)N1CCC(CC1)c1cc(NC(=O)c2cccc(c2)-c2ccn[nH]2)n(n1)-c1ccccn1

InChI Key InChIKey=KLAHVJUJQYVKPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 588181   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588181(US11542251, Compound TL1)
Affinity DataIC50: 3nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588181(US11542251, Compound TL1)
Affinity DataIC50: 7nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent