BDBM589753 US11559538, Example 16::US11559538, Example 208::US11559538, Example 48

SMILES CCCOc1nc(c(F)cc1OC)-c1cncc(c1)C1COB(O)C1

InChI Key InChIKey=CECUZGKZZDAYHR-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 589753   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM589753(US11559538, Example 16 | US11559538, Example 208 |...)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of human PDE4 catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed

LigandPNGBDBM589753(US11559538, Example 16 | US11559538, Example 208 |...)
Affinity DataIC50:  0.220nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589753(US11559538, Example 16 | US11559538, Example 208 |...)
Affinity DataIC50:  1.81E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589753(US11559538, Example 16 | US11559538, Example 208 |...)
Affinity DataIC50:  4.06nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589753(US11559538, Example 16 | US11559538, Example 208 |...)
Affinity DataIC50:  1.98nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM589753(US11559538, Example 16 | US11559538, Example 208 |...)
Affinity DataIC50:  0.0500nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589753(US11559538, Example 16 | US11559538, Example 208 |...)
Affinity DataIC50:  0.980nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589753(US11559538, Example 16 | US11559538, Example 208 |...)
Affinity DataIC50:  0.540nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589753(US11559538, Example 16 | US11559538, Example 208 |...)
Affinity DataIC50:  0.820nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM589753(US11559538, Example 16 | US11559538, Example 208 |...)
Affinity DataIC50:  0.120nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589753(US11559538, Example 16 | US11559538, Example 208 |...)
Affinity DataIC50:  252nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589753(US11559538, Example 16 | US11559538, Example 208 |...)
Affinity DataIC50:  0.820nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589753(US11559538, Example 16 | US11559538, Example 208 |...)
Affinity DataIC50:  126nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent