BDBM589871 US11559538, Example 125::US11559538, Example 126

SMILES COc1ccc(cc1OC1CCCC1)-c1cncc(n1)C1COB(O)C1

InChI Key InChIKey=AYEOPFJMOQXCHK-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589871   

LigandPNGBDBM589871(US11559538, Example 125 | US11559538, Example 126)
Affinity DataIC50:  1.70nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589871(US11559538, Example 125 | US11559538, Example 126)
Affinity DataIC50:  577nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589871(US11559538, Example 125 | US11559538, Example 126)
Affinity DataIC50:  11.3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589871(US11559538, Example 125 | US11559538, Example 126)
Affinity DataIC50:  0.790nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM589871(US11559538, Example 125 | US11559538, Example 126)
Affinity DataIC50:  0.850nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589871(US11559538, Example 125 | US11559538, Example 126)
Affinity DataIC50:  680nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589871(US11559538, Example 125 | US11559538, Example 126)
Affinity DataIC50:  7.21nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589871(US11559538, Example 125 | US11559538, Example 126)
Affinity DataIC50:  2.43nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent