BDBM589886 US11559538, Example 138::US11559538, Example 139::US11559538, Example 140

SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C(F)F

InChI Key InChIKey=YYHIGCRTQLFVLJ-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 589886   

LigandPNGBDBM589886(US11559538, Example 138 | US11559538, Example 139 ...)
Affinity DataIC50:  2.04nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589886(US11559538, Example 138 | US11559538, Example 139 ...)
Affinity DataIC50:  988nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589886(US11559538, Example 138 | US11559538, Example 139 ...)
Affinity DataIC50:  1.08nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589886(US11559538, Example 138 | US11559538, Example 139 ...)
Affinity DataIC50:  0.900nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM589886(US11559538, Example 138 | US11559538, Example 139 ...)
Affinity DataIC50:  0.25nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589886(US11559538, Example 138 | US11559538, Example 139 ...)
Affinity DataIC50:  3.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589886(US11559538, Example 138 | US11559538, Example 139 ...)
Affinity DataIC50:  0.780nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589886(US11559538, Example 138 | US11559538, Example 139 ...)
Affinity DataIC50:  0.400nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM589886(US11559538, Example 138 | US11559538, Example 139 ...)
Affinity DataIC50:  2.70nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589886(US11559538, Example 138 | US11559538, Example 139 ...)
Affinity DataIC50:  3.45E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589886(US11559538, Example 138 | US11559538, Example 139 ...)
Affinity DataIC50:  3.47nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589886(US11559538, Example 138 | US11559538, Example 139 ...)
Affinity DataIC50:  788nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent