BDBM590277 US11560385, Compound 52B

SMILES Cc1c(C(=O)CN2C3CCC2[C@@H](O)C3)cc(/C=C/CC2CC(C)(C)OC2=O)n1-c1ccc(C#N)cc1

InChI Key InChIKey=SZYNUVWSQMDPLO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 590277   

TargetUbiquitin carboxyl-terminal hydrolase 14(Human)
Proteostasis Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 590277BDBM590277(US11560385, Compound 52B)
Affinity DataIC50: 50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent