BDBM590649 US11560381, Compound D448

SMILES [#6]-[#8]-c1cc(cc(-[#8]-[#6])c1-[#6]-[#7]-1-[#6]-[#6](-[#6]-[#6]-c2ccc3-[#6]-[#7](-[#6]-4-[#6]-[#6]-[#6](=O)-[#7]-[#6]-4=O)-[#6](=O)-c3c2)-[#6]-1)-c1cc(-[#6])c(=O)n(-[#6])c1

InChI Key InChIKey=RGPRUVIDZLPWSF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 590649   

TargetProtein SSX2/Protein SSXT(Human)
Foghorn Therapeutics

US Patent
LigandPNGBDBM590649(US11560381, Compound D448)
Affinity DataIC50: 10nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent