BDBM590666 US11560381, Compound D465

SMILES C\C=C\Cn1cc(-c2ccc(CN3CCC4(CN(C4)c4ccc5CN(C6CCC(=O)NC6=O)C(=O)c5c4)CC3)c(Cl)c2)n2cncc2c1=O

InChI Key InChIKey=XRHGIJPJPOKWOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 590666   

TargetProtein SSX2/Protein SSXT(Human)
Foghorn Therapeutics

US Patent
LigandPNGBDBM590666(US11560381, Compound D465)
Affinity DataIC50: 10nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent