BDBM591148 US11566003, Compound 53::tetrahydro-2H-pyran-4-yl (8-amino- 6-(5-amino-4-methylpyridin-3-yl)-7- fluoroisouinolin-3-carbamate- yl)carbamate

SMILES Cc1c(N)cncc1-c1cc2cc(NC(=O)OC3CCOCC3)ncc2c(N)c1F

InChI Key InChIKey=GGPIVPOCOTXSNM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 591148   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM591148(US11566003, Compound 53 | tetrahydro-2H-pyran-4-yl...)
Affinity DataKi:  0.0200nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent