BDBM591273 US11566003, Compound 340
SMILES C[C@@H]1[C@@H]([C@H]1c1cnn(CC(F)F)c1)C(=O)Nc1cc2cc(c(F)c(N)c2cn1)-c1cnccc1C
InChI Key InChIKey=POUDWBQSFSIFGQ-QYDGOFIISA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 591273
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: 0.0200nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair