BDBM592107 US11566028, Example 46

SMILES CCS(=O)(=O)c1cc(F)c(F)c(c1)-c1cnn2cc(-c3cnn(C)c3)c(O[C@H]3CCOC3)nc12

InChI Key InChIKey=HBWKMUJLBPOVOZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 592107   

TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM592107(US11566028, Example 46)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM592107(US11566028, Example 46)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM592107(US11566028, Example 46)
Affinity DataIC50: 20nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent
LigandPNGBDBM592107(US11566028, Example 46)
Affinity DataIC50: 200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2023
Entry Details
US Patent