BDBM592112 US11566028, Example 51

SMILES Cn1cc(cn1)-c1cn2ncc(-c3cccc(c3)-c3cc[nH]n3)c2nc1O[C@H]1CCOC1

InChI Key InChIKey=HQKIDOSUESTUGG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 592112   

TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM592112(US11566028, Example 51)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM592112(US11566028, Example 51)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM592112(US11566028, Example 51)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent
LigandPNGBDBM592112(US11566028, Example 51)
Affinity DataIC50: 200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2023
Entry Details
US Patent