BDBM593028 4-(((1R,4R)-4- aminocyclohexyl)methoxy)-5- fluoro-N-(4- morpholinophenyl)pyrimidin-2- amine::US11578061, Example 10

SMILES N[C@H]1CC[C@H](COc2nc(Nc3ccc(cc3)N3CCOCC3)ncc2F)CC1

InChI Key InChIKey=MWUSIZRYHPRCQN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593028   

LigandPNGBDBM593028(4-(((1R,4R)-4- aminocyclohexyl)methoxy)-5- fluoro-...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent