BDBM593035 4-(((1R,3S)-3- aminocyclopentyl)methoxy)-5- chloro-N-(4- morpholinophenyl)pyrimidin-2- amine::US11578061, Example 16

SMILES N[C@H]1CC[C@@H](COc2nc(Nc3ccc(cc3)N3CCOCC3)ncc2Cl)C1

InChI Key InChIKey=SVIVSYJSTKEKCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593035   

LigandPNGBDBM593035(4-(((1R,3S)-3- aminocyclopentyl)methoxy)-5- chloro...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent