BDBM593044 3-(4-((5-chloro-4-((4- fluoropiperidin-4- yl)methoxy)pyrimidin-2- yl)amino)-5-methyl-1H-pyrazol-1- yl)cyclobutane-1-carbonitrile::US11578061, Example 22

SMILES Cc1c(Nc2ncc(Cl)c(OCC3(F)CCNCC3)n2)cnn1C1CC(C1)C#N

InChI Key InChIKey=XBYJPCOFYHJUMN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593044   

LigandPNGBDBM593044(3-(4-((5-chloro-4-((4- fluoropiperidin-4- yl)metho...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent