BDBM593045 N-(4-((2R,6S)-2,6- dimethylmorpholino)phenyl)-5- fluoro-4-((4-fluoropiperidin-4- yl)methoxy)pyrimidin-2-amine::US11578061, Example 23

SMILES C[C@H]1CN(C[C@@H](C)O1)c1ccc(Nc2ncc(F)c(OCC3(F)CCNCC3)n2)cc1

InChI Key InChIKey=UOUKVBTYQFHABW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593045   

LigandPNGBDBM593045(N-(4-((2R,6S)-2,6- dimethylmorpholino)phenyl)-5- f...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent