BDBM593109 N-((1R,4R)-4-(((2-((1-(2- cyanopropan-2-yl)-3-methyl-1H- pyrazol-4-yl)amino)-5- methylpyrimidin-4- yl)oxy)methyl)cyclohexyl) acetamide::US11578061, Example 87
SMILES CC(=O)N[C@H]1CC[C@H](COc2nc(Nc3cn(nc3C)C(C)(C)C#N)ncc2C)CC1
InChI Key InChIKey=KUMLVPOADRGTPG-IYARVYRRSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 593109
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [970-2527](Human)
Halia Therapeutics
US Patent
Halia Therapeutics
US Patent
Affinity DataIC50: <50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair