BDBM593227 N-((1R,4R)-4-(((2-((5-chloro-1-(2- methoxyethyl)-1H-pyrazol-4- yl)amino)-5-fluoropyrimidin-4- yl)oxy)methyl)cyclohexyl) acetamide::US11578061, Example 205

SMILES COCCn1ncc(Nc2ncc(F)c(OC[C@H]3CC[C@@H](CC3)NC(C)=O)n2)c1Cl

InChI Key InChIKey=NENDOZTVIUJTIN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593227   

LigandPNGBDBM593227(N-((1R,4R)-4-(((2-((5-chloro-1-(2- methoxyethyl)-1...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent